Why can't White Feces Syndrome (WFS) be cured with antibiotics alone?

WFS is MULTI-CAUSAL — combining EHP, Vibrio, parasites and gut dysbiosis (Aranguren et al., 2021). No single drug cures it; a healthy microbiome and multi-layer control before outbreak are required.

What is the postbiotic in Bio Max and how does it differ from a probiotic?

A postbiotic (ISAPP 2021 consensus) contains INACTIVATED microbes plus metabolites (organic acids, peptides, exopolysaccharides) — no live cells needed, active on gut contact: protecting tight junctions, preventing leaky gut, stimulating beneficial Bifidobacteria within 24h.

What are the 3 microbiome layers in the Microbiome Farm protocol?

Three parallel layers: (1) POND — FYTO FLOC, SOILMAX New, MAX 4000, OZYME decompose organics, suppress Vibrio, remove NH3/NO2/H2S; (2) GUT — BIO MAX, PRO SUR, PRO GUT, FLASH, CLEVER, ACTISEL displace pathogens; (3) HOST — HERB GUARD, AQUAMOS, CANFORTA, CELL CANPHOS GOLD, CALPHOS GRO protect the hepatopancreas, boost immunity and supply minerals.

How fast is liquid mineral CELL CANPHOS GOLD absorbed?

Applied at 1kg/1,000m³ — pre-ionised Ca²⁺/Mg²⁺ is PASSIVELY absorbed via the gills within 2–4 hours, combined with CALPHOS GRO in feed at 3–5ml/kg for gut minerals. Chelated organic minerals absorb better than common inorganic ones.

Official technical document

Microbiome Farm Protocol

Prevention beats treatment — by building a microbial ecosystem across the entire crop.

05
challenges farmers face: 03
layers that keep the pond stable: 04
crop stages: 05
solution pillars

Version: 2026.04·For: Whiteleg shrimp (P. vannamei) + Black tiger shrimp

The full document covers:1. Challenges 2. Three layers, one stable pond 3. Crop map 4. 5 solution pillars 5. Customer success 6. References

Overview video · 42 seconds

01/ 06

Challenges shrimp farmers face

Five challenges weigh on the shrimp industry, and they are not the same kind.

Section 01 in 38 seconds

Key points

Three diseases come from a single agent (WSD, EMS, TPD) — name it and you can block it.
EHP works quietly: shrimp still live and eat, they just grow slowly and weaken.
WFS — the most common — is the sum of several causes, EHP among them.
No single drug solves WFS: build a healthy microbiome before the outbreak.

WSD

White Spot Disease

EMS

Early Mortality Syndrome

TPD

Translucent Postlarvae Disease

EHP

Hepatopancreatic microsporidiosis

⚠ No obvious signs

WFS

White Feces Syndrome

⚠ Multi-causal

Next02 · Three layers, one stable pondThe pathogens are always there. So what decides whether they act?

02/ 06

Three layers keep the pond in the stable zone

Disease does not erupt because pathogens appear, but because the pond slides out of its stable zone.

Section 02 in 40 seconds

Key points

Pathogens are almost always in the pond — disease erupts when the pond slides out of its stable zone.
Three layers work at once: the pond water, the shrimp gut and the shrimp itself.
In the gut, the ratio of beneficial, opportunistic and pathogenic bacteria decides whether shrimp thrive.
The three layers run in parallel, not as substitutes — drop one and the other two cannot carry it.

POND

Pond bottom & water microbiome

FYTO FLOC + SOILMAX New + MAX 4000 + OZYME

GUT

Shrimp gut microbiome

BIO MAX + PRO SUR + PRO GUT + FLASH + CLEVER + ACTISEL

HOST

Host (shrimp) support

HERB GUARD + AQUAMOS + CANFORTA + CELL CANPHOS GOLD + CALPHOS GRO

Low riskhigh diversity — the pond recovers fast after a shock, outbreaks are rarer
Rising riskdiversity slipping — recovery weakens and risk creeps up
High risklow diversity — the pond struggles to recover and outbreaks come easily

POND WATER

SHRIMP GUT

GIT5
GIT6

The horizontal axis counts days from the FIRST SAMPLING, not from stocking. Monitoring data from ponds running the protocol: both the pond water and the shrimp gut hold their diversity index in the low-risk zone throughout. Values digitised from the original monitoring chart.

A closer look at the GUT layer

Side view of a whiteleg shrimp with the gut highlighted in orange along the back and the hepatopancreas behind the head in dark red. — The two places that decide shrimp health sit next to each other: the gut running along the back and the hepatopancreas just behind the head.

The shrimp gut holds

Yeasts
Protozoa
Viruses
Bacteria

All four are present. But the group that decides whether the pond holds or collapses is BACTERIA — and it is also the only one a farmer can steer, through feed and probiotics.

Beneficial

Bacillus
Lactococcus
Lactobacillus
Pediococcus
Bifidobacterium
Rhodopseudomonas

Opportunistic

Pseudomonas
Flavobacterium

Pathogenic

Vibrio parahaemolyticus
Vibrio harveyi
EHP

Reference: Cornejo-Granados et al., 2017 — Scientific Reports

In-depth edition

4 more sections in the in-depth edition

The part above answers “why”. The in-depth edition answers “how” — free to read, no sign-up.

Read the in-depth edition →

Balance the three and the pond holdsDynamic diagram: the pond's stable basin vs. its wobble ridge.
Crop mapOne picture: which job sits in which layer, when, and the goal of each stage.
5 Microbio Farm pillarsPostbiotic + specialized probiotics, gut health, hepatopancreas & immunity, EHP control, absorbable minerals.
Customer successReal pond results from farmers already running it.
ReferencesThe studies behind the protocol, with lookup-able DOIs.

Challenges shrimp farmers face

Key points

White Spot Disease

Early Mortality Syndrome

Translucent Postlarvae Disease

Hepatopancreatic microsporidiosis

White Feces Syndrome

Three layers keep the pond in the stable zone

Key points

Pond bottom & water microbiome

Shrimp gut microbiome

Host (shrimp) support

A closer look at the GUT layer

Beneficial

Opportunistic

Pathogenic

4 more sections in the in-depth edition

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